Cellular injury evidenced by impedance technology and infrared microspectroscopy

Cellular injury evidenced by impedance technology and infrared microspectroscopy.

Fourier Transform Infrared (FTIR) spectroscopy is finding increasing biological application, for example in the analysis of diseased tissues and cells, cell cycle studies and investigating the mechanisms of action of anticancer drugs. Cancer treatment studies routinely define the types of cell-drug responses as either total cell destruction by the drug (all cells die), moderate damage (cell det...

Single Cancer Cell Detection by Near Infrared Microspectroscopy, Infrared Chemical Imaging and Fluorescence Microspectroscopy

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From structure to cellular mechanism with infrared microspectroscopy.

Current efforts in structural biology aim to integrate structural information within the context of cellular organization and function. X-rays and infrared radiation stand at opposite ends of the electromagnetic spectrum and act as complementary probes for achieving this goal. Intense and bright beams are produced by synchrotron radiation, and are efficiently used in the wavelength domain exten...

Infrared microspectroscopy in biological research.

Analysis of latent fingerprint deposits by infrared microspectroscopy.

We report the use of infrared (IR) microspectroscopy for the analysis of fingerprint residues. The advantage of using an IR microscope lies in the ability to visualize and obtain spectra of individual particles and droplets that make up fingerprint ridge deposits at a spatial resolution of approximately 10 microm. Our initial results suggest that infrared microspectroscopy in reflection-absorpt...